Each of the ciliary ganglion has various dedicated fibers. This is more likely if the damage that occurred affected the ciliary body instead of the ciliary ganglion. It is possible to experience partial function recovery if full recovery does not occur. Some people never experience full recovery of their pupillary response. In some cases, the pupil that was once larger actually goes in the opposite direction and becomes smaller than the other pupil. Within two years, approximately 50 percent of people with anisocoria experience a full recovery. For many cases of this condition, there is no known effective treatment. There is not a treatment specific to Horner’s syndrome. If an underlying cause is identified, treatment is aimed at this issue. However, the cause is not always identified. Most cases of this syndrome have an underlying cause, such as a tumor, stroke, or spinal cord injury. It is characterized by a triad of symptoms, including pupil constriction that causes anisocoria, drooping eyelid, and not sweating in the area surrounding the affected eye. Horner’s syndrome is another possible cause of anisocoria. Certain medications that go directly into the eye, such as glaucoma eyedrops like pilocarpine.Eye trauma from accidental injury or surgery.Certain brain disorders and injuries, such as a stroke, brain tumor, brain hemorrhage, or infection in the brain.When the issue is significant, multiple factors can cause it.Some research suggests that mild anisocoria affects about 20 percent of the general population. In many cases, when this issue is mild, there is no underlying cause. Over time, it is possible for both of the pupils to be affected. When Adie syndrome is present, it usually starts by affecting one pupil. Facial pain, headache, and emotional fluctuations are also possible with this condition. When a doctor tests the person’s deep tendon reflexes using a small hammer, they either do not have any response or the response is poor. When this issue occurs as a result of Adie syndrome, people often have poor or absent deep tendon reflexes too. Some examples of accompanying symptoms include the following: The underlying cause of this condition ultimately determines the other symptoms that a person experiences. But people can experience it on a regular basis too. In some cases, this condition is only temporary. The doctor usually picks up on the problem when they are giving an eye examination. In many cases, people do not notice that their pupils are unequal because the size difference is not significant. This means that it starts losing its color and can become lighter. It is also possible for the iris to experience depigmentation. This is referred to as anisocoria.īy looking at the affected pupil, you can sometimes see that it is larger than the other pupil. But for some people, the pupils are not always the same size. For most people, the pupils react to light, either enlarging or shrinking equally. The black spot in the center of your eye is known as the pupil. A doctor will perform an examination to determine if treatment is necessary. ![]() But if uneven pupils are the result of a medical condition, treatment might be necessary. In benign cases where the issue just occurs for no apparent reason, no treatment is necessary. ![]() While it is often a benign issue, it is also possible for it to be a symptom of a medical condition. In fact, it happens in about one in five people. 2003 110(8):1606-14.Īmerican Academy of Ophthalmology.It’s common to have pupils that are different sizes. Pupil size and quality of vision after LASIK. Schallhorn SC, Kaupp SE, Tanzer DJ, Tidwell J, Laurent J, Bourque LB. Ocular manifestations of drug and alcohol abuse. Pupillary reactivity as an early indicator of increased intracranial pressure: the introduction of the Neurological Pupil index. doi:10.3892/ol.2017.5648Ĭhen JW, Gombart ZJ, Rogers S, Gardiner SK, Cecil S, Bullock RM. Iris metastasis as the first sign of small cell lung cancer: a case report. March 23, 2016.īrigham And Women's Hospital. Pupillary disorders including anisocoria.Īmerican Academy of Ophthalmology. What kinds of eye examinations are there? April 20, 2016. Anisocoria and an array of neurologic symptoms in an adult with Ewing sarcoma. Safe and sensible preprocessing and baseline correction of pupil-size data. Mathôt S, Fabius J, Van Heusden E, Van der Stigchel S. A model of the entrance pupil of the human eye.
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